Diffuse intrinsic pontine glioma (DIPG) is a rare, fast-growing, and aggressive brain tumor that forms in the brainstem of children. It's the leading cause of brain tumor-related deaths in children, with about 200 to 300 new cases in the United States each year. DIPG is hard to treat and has a poor prognosis. Without treatment, most children survive six months after diagnosis, and less than 10% survive more than two years. Radiation therapy can extend survival to nine to 11 months on average.